Translation

 Background knowledge

• The complete mRNA leave the nucleus and goes into the  cytoplasm
• polypeptide= many proteins
• The goal of translation is to create proteins

Act I
Initiation:



tRNA forms a complex with the with the ribosomal sub units
 this complex then binds with mRNA at the 5' cap and scans the mRNA

transfer RNA brings amino acids that correspond to the codons on mRNA
tRNA recognizes these codons by the anticodon loop attached to it
The starter codon is AUG which corresponds with the amino acid Methionine , the anticodon loop for it is UAC

Elongation
The polypeptide becomes longer one amino acid at a time
The first tRNA carrying the starter amino acid AUG goes to the P site
when the next tRNA brings the amino acid the previous tRNA goes to the E site

Termination
The codons UCC, UCA, UCG, UCU have no corresponding tRNA sequence so this process stops
Now the termination proteins release the ribosome from the mRNA, the polypeptide chain is released